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Tag: transcriptional regulation

Genome Functions in Space and Time

Our group is affiliated with UMR3664 and UMR168. We currently have openings. More info on our website: www.coulonlab.org Our goal is to understand the two-way relationship between the spatio-temporal organization and dynamics of the genome and the coordinated regulation of its expression – through an approach at the interface between physics, computer science and biology. The […]

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Epigenetic plasticity and polarity of the embryo

Our work aims to elucidate how cells acquire and maintain their identity during development. This question is particularly critical in the context of cancer as, in tumors, cells have very frequently changed their identity. As in eukaryotes the “epigenome” predominantly determines cellular identity, we focus on the role of chromatin dynamics to maintain genome integrity […]

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