asymmetric cell division Archives - Centre de recherche de l'Institut Curie

Polarity Division Morphogenesis

Cell polarity is fundamental to the development of multi-cellular organisms, playing a central role in proliferation, cell fate diversification and tissue homeostasis or morphogenesis. The mechanisms controlling cell polarization are conserved, and the Drosophila fruit fly model has played a leading role in helping our understanding of the mechanisms controlling cell polarization during development. Our […]

Biology of centrosomes and genetic instability

Known as the main microtubule organizing center of animal cells (MTOCs), the centrosome participates in the organization of the microtubule network within the cell. It is formed of two centrioles surrounded by a structured matrix of proteins called the pericentriolar material (PCM). While the centrioles are involved in the recruitment of the proteins that form […]