Systems Biology of Cell Polarity and Cell Division

Team Members

Matthieu Piel, PhD

Matthieu Piel

Matthieu Piel CNRS Research Director Team Piel Team Leader Tel:

Research Gate
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Biography

2018 : CNRS (DR1), UMR 144 Institut Curie, IPGG
2014 : CNRS (DR2), UMR 144 Institut Curie
2005 : CNRS (CR2), UMR 144 Institut Curie
2002-2005 : Post doc in Prof. Andrew Murray's lab, Harvard University MCB Cambridge USA. Subject : «Etude quantitative de la réponse des levures de boulanger à la phéromone sexuelle: de la microfluidique à la conjugaison.»
1997-2002 : PhD in Dr. Michel Bornens's lab, Institut Curie, UMR 144 Paris FRANCE. Subject: «Etude cinetique et fonctionnelle du centrosome des cellules de Vertébré».
1996-1997 : DEA Physique des Liquides, Université Paris-VI, Option Polymères et Cristaux Liquides 1993-1996 : Ecole Polytechnique, Option Physique Expérimentale et Biophysique

 Awards

2016 : EMBO Membership
2012 : Médaille de Bronze du CNRS
2002 : Prix Nine Choucroun

 Patent

Bornens M, Thery M and Piel M (2004) Methods and Device for Adhesive Control of Internal Cell Organization. # PCT/1B2003/003091

Key publications

Year of publication 2019

Matteo Gentili, Xavier Lahaye, Francesca Nadalin, Guilherme P F Nader, Emilia Puig Lombardi, Solène Herve, Nilushi S De Silva, Derek C Rookhuizen, Elina Zueva, Christel Goudot, Mathieu Maurin, Aurore Bochnakian, Sebastian Amigorena, Matthieu Piel, Daniele Fachinetti, Arturo Londoño-Vallejo, Nicolas Manel (2019 Mar 28)

The N-Terminal Domain of cGAS Determines Preferential Association with Centromeric DNA and Innate Immune Activation in the Nucleus.

Cell reports : 3798 : DOI : S2211-1247(19)30365-1

Year of publication 2016

Hawa-Racine Thiam, Pablo Vargas, Nicolas Carpi, Carolina Lage Crespo, Matthew Raab, Emmanuel Terriac, Megan C King, Jordan Jacobelli, Arthur S Alberts, Theresia Stradal, Ana-Maria Lennon-Dumenil, Matthieu Piel (2016 Mar 16)

Perinuclear Arp2/3-driven actin polymerization enables nuclear deformation to facilitate cell migration through complex environments.

Nature communications : 10997 : DOI : 10.1038/ncomms10997
Pablo Vargas, Paolo Maiuri, Marine Bretou, Pablo J Sáez, Paolo Pierobon, Mathieu Maurin, Mélanie Chabaud, Danielle Lankar, Dorian Obino, Emmanuel Terriac, Matthew Raab, Hawa-Racine Thiam, Thomas Brocker, Susan M Kitchen-Goosen, Arthur S Alberts, Praveen Sunareni, Sheng Xia, Rong Li, Raphael Voituriez, Matthieu Piel, Ana-Maria Lennon-Duménil (2016 Jan 8)

Innate control of actin nucleation determines two distinct migration behaviours in dendritic cells.

Nature cell biology : 43-53 : DOI : 10.1038/ncb3284

Year of publication 2015

Paolo Maiuri, Jean-François Rupprecht, Stefan Wieser, Verena Ruprecht, Olivier Bénichou, Nicolas Carpi, Mathieu Coppey, Simon De Beco, Nir Gov, Carl-Philipp Heisenberg, Carolina Lage Crespo, Franziska Lautenschlaeger, Maël Le Berre, Ana-Maria Lennon-Dumenil, Matthew Raab, Hawa-Racine Thiam, Matthieu Piel, Michael Sixt, Raphaël Voituriez (2015 Apr 9)

Actin flows mediate a universal coupling between cell speed and cell persistence.

Cell : 374-86 : DOI : 10.1016/j.cell.2015.01.056

Year of publication 2014

Ana Joaquina Jimenez, Paolo Maiuri, Julie Lafaurie-Janvore, Séverine Divoux, Matthieu Piel, Franck Perez (2014 Jan 30)

ESCRT machinery is required for plasma membrane repair.

Science (New York, N.Y.) : 1247136 : DOI : 10.1126/science.1247136

Year of publication 2011

Maria-Isabel Fernandez, Mélina L Heuzé, Carolina Martinez-Cingolani, Elisabetta Volpe, Marie-Helene Donnadieu, Matthieu Piel, Bernhard Homey, Ana-Maria Lennon-Duménil, Vassili Soumelis (2011 Jul 19)

The human cytokine TSLP triggers a cell-autonomous dendritic cell migration in confined environments.

Blood : 3862-9 : DOI : 10.1182/blood-2010-12-323089

Year of publication 2008

Gabrielle Faure-André, Pablo Vargas, Maria-Isabel Yuseff, Mélina Heuzé, Jheimmy Diaz, Danielle Lankar, Veronica Steri, Jeremy Manry, Stéphanie Hugues, Fulvia Vascotto, Jérôme Boulanger, Graça Raposo, Maria-Rosa Bono, Mario Rosemblatt, Matthieu Piel, Ana-Maria Lennon-Duménil (2008 Dec 17)

Regulation of dendritic cell migration by CD74, the MHC class II-associated invariant chain.

Science (New York, N.Y.) : 1705-10 : DOI : 10.1126/science.1159894