Tumor Microenvironment Laboratory 

Members

Giorgio Seano, PhD

Seano Giorgio-Uriel Chantraine Institut Curie

Giorgio Seano Researcher Team Seano Team Leader Tel: Back to the list

CV Giorgio SEANO

Key publications

Year of publication 2019

Giorgio Seano, Rakesh K Jain (2019 Nov 4)

Vessel co-option in glioblastoma: emerging insights and opportunities.

Angiogenesis : DOI : 10.1007/s10456-019-09691-z
Giorgio Seano, Hadi T Nia, Kyrre E Emblem, Meenal Datta, Jun Ren, Shanmugarajan Krishnan, Jonas Kloepper, Marco C Pinho, William W Ho, Mitrajit Ghosh, Vasileios Askoxylakis, Gino B Ferraro, Lars Riedemann, Elizabeth R Gerstner, Tracy T Batchelor, Patrick Y Wen, Nancy U Lin, Alan J Grodzinsky, Dai Fukumura, Peigen Huang, James W Baish, Timothy P Padera, Lance L Munn, Rakesh K Jain (2019 Apr 6)

Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium.

Nature biomedical engineering : 230-245 : DOI : 10.1038/s41551-018-0334-7
John D Martin, Giorgio Seano, Rakesh K Jain (2019 Feb 12)

Normalizing Function of Tumor Vessels: Progress, Opportunities, and Challenges.

Annual review of physiology : 505-534 : DOI : 10.1146/annurev-physiol-020518-114700

Year of publication 2018

Amelie Griveau, Giorgio Seano, Samuel J Shelton, Robert Kupp, Arman Jahangiri, Kirsten Obernier, Shanmugarajan Krishnan, Olle R Lindberg, Tracy J Yuen, An-Chi Tien, Jennifer K Sabo, Nancy Wang, Ivy Chen, Jonas Kloepper, Louis Larrouquere, Mitrajit Ghosh, Itay Tirosh, Emmanuelle Huillard, Arturo Alvarez-Buylla, Michael C Oldham, Anders I Persson, William A Weiss, Tracy T Batchelor, Anat Stemmer-Rachamimov, Mario L Suvà, Joanna J Phillips, Manish K Aghi, Shwetal Mehta, Rakesh K Jain, David H Rowitch (2018 Apr 24)

A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment.

Cancer cell : DOI : 10.1016/j.ccell.2018.03.020
Ethel R Pereira, Dmitriy Kedrin, Giorgio Seano, Olivia Gautier, Eelco F J Meijer, Dennis Jones, Shan-Min Chin, Shuji Kitahara, Echoe M Bouta, Jonathan Chang, Elizabeth Beech, Han-Sin Jeong, Michael C Carroll, Alphonse G Taghian, Timothy P Padera (2018 Mar 24)

Lymph node metastases can invade local blood vessels, exit the node, and colonize distant organs in mice.

Science (New York, N.Y.) : 1403-1407 : DOI : 10.1126/science.aal3622
Giorgio Seano (2017 Nov 15)

Targeting the perivascular niche in brain tumors.

Current opinion in oncology : 54-60 : DOI : 10.1097/CCO.0000000000000417

Year of publication 2016

Teresa E Peterson, Nathaniel D Kirkpatrick, Yuhui Huang, Christian T Farrar, Koen A Marijt, Jonas Kloepper, Meenal Datta, Zohreh Amoozgar, Giorgio Seano, Keehoon Jung, Walid S Kamoun, Trupti Vardam, Matija Snuderl, Jermaine Goveia, Sampurna Chatterjee, Ana Batista, Alona Muzikansky, Ching Ching Leow, Lei Xu, Tracy T Batchelor, Dan G Duda, Dai Fukumura, Rakesh K Jain (2016 Apr 5)

Dual inhibition of Ang-2 and VEGF receptors normalizes tumor vasculature and prolongs survival in glioblastoma by altering macrophages.

Proceedings of the National Academy of Sciences of the United States of America : 4470-5 : DOI : 10.1073/pnas.1525349113

Year of publication 2014

Giorgio Seano, Giulia Chiaverina, Paolo Armando Gagliardi, Laura di Blasio, Alberto Puliafito, Claire Bouvard, Roberto Sessa, Guido Tarone, Lydia Sorokin, Dominique Helley, Rakesh K Jain, Guido Serini, Federico Bussolino, Luca Primo (2014 Sep 15)

Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis.

Nature cell biology : 931-41, 1-8 : DOI : 10.1038/ncb3036

Year of publication 2013

Giorgio Seano, Giulia Chiaverina, Paolo Armando Gagliardi, Laura di Blasio, Roberto Sessa, Federico Bussolino, Luca Primo (2013 Mar 9)

Modeling human tumor angiogenesis in a three-dimensional culture system.

Blood : e129-37 : DOI : 10.1182/blood-2012-08-452292

Year of publication 2010

Luca Primo, Giorgio Seano, Cristina Roca, Federica Maione, Paolo Armando Gagliardi, Roberto Sessa, Marianna Martinelli, Enrico Giraudo, Laura di Blasio, Federico Bussolino (2010 Jun 24)

Increased expression of alpha6 integrin in endothelial cells unveils a proangiogenic role for basement membrane.

Cancer research : 5759-69 : DOI : 10.1158/0008-5472.CAN-10-0507