Signaling and Cancer progression

Team Members

Alain Eychène, PhD

Eychène

Alain Eychène Inserm Research Director Team Eychène/Pouponnot Team Leader Tel: Back to the list

Curriculum vitae

Key publications

Year of publication 2019

Morabito Morgane, Larcher Magalie, Cavalli Florence MG, Foray Chloé, Forget Antoine, Mirabal-Ortega Liliana , Andrianteranagna Mamy, Druillennec Sabine, Garancher Alexandra, Masliah-Planchon Julien, Leboucher Sophie, Debalkew Abel, Raso Alessandro, Delattre Olivier , Puget Stéphanie, Doz François, Taylor Michael D, Ayrault Olivier, Bourdeaut Franck, Eychène Alain & Pouponnot Celio (2019 Jul 22)

An autocrine ActivinB mechanism drives TGFb/Activin signaling in Group3medulloblastoma

EMBO Molecular Medecine : 11 : e9830 : DOI : 10.15252/emmm.201809830

Year of publication 2018

Alexandra Garancher, Charles Y Lin, Morgane Morabito, Wilfrid Richer, Nathalie Rocques, Magalie Larcher, Laure Bihannic, Kyle Smith, Catherine Miquel, Sophie Leboucher, Nirmitha I Herath, Fanny Dupuy, Pascale Varlet, Christine Haberler, Christine Walczak, Nadine El Tayara, Andreas Volk, Stéphanie Puget, François Doz, Olivier Delattre, Sabine Druillennec, Olivier Ayrault, Robert J Wechsler-Reya, Alain Eychène, Franck Bourdeaut, Paul A Northcott, Celio Pouponnot (2018 Mar 14)

NRL and CRX Define Photoreceptor Identity and Reveal Subgroup-Specific Dependencies in Medulloblastoma.

Cancer cell : 435-449.e6 : DOI : 10.1016/j.ccell.2018.02.006

Year of publication 2017

Coralie Dorard, Charlène Estrada, Céline Barbotin, Magalie Larcher, Alexandra Garancher, Jessy Leloup, Friedrich Beermann, Manuela Baccarini, Celio Pouponnot, Lionel Larue, Alain Eychène, Sabine Druillennec (2017 May 13)

RAF proteins exert both specific and compensatory functions during tumour progression of NRAS-driven melanoma.

Nature communications : 15262 : DOI : 10.1038/ncomms15262

Year of publication 2014

N I Herath, N Rocques, A Garancher, A Eychène, C Pouponnot (2014 Jan 21)

GSK3-mediated MAF phosphorylation in multiple myeloma as a potential therapeutic target.

Blood cancer journal : e175 : DOI : 10.1038/bcj.2013.67

Year of publication 2012

Agathe Valluet, Sabine Druillennec, Céline Barbotin, Coralie Dorard, Anne H Monsoro-Burq, Magalie Larcher, Celio Pouponnot, Manuela Baccarini, Lionel Larue, Alain Eychène (2012 Oct 2)

B-Raf and C-Raf are required for melanocyte stem cell self-maintenance.

Cell reports : 774-80 : DOI : 10.1016/j.celrep.2012.08.020