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Unit
ANTONIN MORILLON / VALERIE BORDE
Dynamics of Genetic Information: fundamental bases and cancer (DIG-Cancer) (UMR3244)

The teams in this unit aim to better understand the mechanisms that maintain genome and epigenome integrity and expression and study how disruptions in these processes contribute to cancers and age-related human diseases.

 

Key figures
123
Publications since 2019
4
ERC since 2019
3
Spin-off since 2019
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Scientific events
30 Apr
2024
Seminar
14h-15h
Demystifying Machine and Deep Learning and overview of their applications in biology
Artificial Intelligence is a broad term that is often misunderstood. Its subfields, such as machine and deep learning have achieved astonishing performances, such as some Large Language Models passing the Turing Test or AlphaFold offering a solution to a 50 years old problem. Because new technologies in medecine and biology generate massive amounts of high quality data (omics, images, clinicals, m
5 Apr
2024
Institutional seminar "Mayent - Rothschild"
11h-12h
A garden of forking paths: branching, switching and reversal in meiotic recombination
Abstract

Meiotic recombination involves repair of double strand DNA breaks by homologous recombination to form crossovers and noncrossovers. Current models suggest that different mechanisms form these two products: noncrossovers by synthesis dependent strand annealing; COs by double Holliday junction formation and resolution. In testing these predictions, we found evidence for remarkable dynami
11 Mar
2024
Symposium
08h-17h
"Genetics together with the next-generation" - A Symposium to celebrate the career of Alain Nicolas
The symposium "Genetics together with the next-generation" will honor the career of Alain Nicolas, dedicated to the study of the mechanisms of genome maintenance and inter-generational transmission. Beyond his numerous scientific contributions, Alain has also contributed to training an important new generation of scientists, gathering the international scientific community through the or
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