Members
Raphaël Margueron, PhD
Raphaël Margueron Team Leader Team CRISPRit Intérim Platform Manager Scientific Director Tel: Back to the list
Key publications
Year of publication 2019
Roberta Ragazzini, Raquel Pérez-Palacios, Irem H Baymaz, Seynabou Diop, Katia Ancelin, Dina Zielinski, Audrey Michaud, Maëlle Givelet, Mate Borsos, Setareh Aflaki, Patricia Legoix, Pascal W T C Jansen, Nicolas Servant, Maria-Elena Torres-Padilla, Deborah Bourc'his, Pierre Fouchet, Michiel Vermeulen, Raphaël Margueron (2019 Aug 26)
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells.
Nature communications : 10 : 1-18 : DOI : 10.1038/s41467-019-11800-x
CAMPAGNE Antoine, LEE Ming-Kang, ZIELINSKI Dina, MICHAUD Audrey, LE CORRE Stéphanie, DINGLI Florent, CHEN Hong, SHAHIDIAN Lara Z, SERVANT Nicolas, LOEW Damarys, PASMANT Eric, PISTEL-VINAY Sophie, WASSEF Michel, MARGUERON Raphaël (2019 Jan 21)
BAP1 complex promotes transcription by opposing PRC1-mediated H2A ubiquitylation
Nature Communications : 10 : 1-15 : DOI : 10.1038/s41467-018-08255-xYear of publication 2018
De Muyt A, Pyatnitskaya A, Andréani J, Ranjha L, Ramus C, Laureau R, Fernandez-Vega A, Holoch D, Girard E, Govin J, Margueron R, Couté Y, Cejka P, Guérois R, Borde V. (2018 Feb 1)
A meiotic XPF-ERCC1-like complex recognizes joint molecule recombination intermediates to promote crossover formation
Genes & Development : DOI : 10.1101/gad.308510.117Year of publication 2017
Manuela Portoso, Roberta Ragazzini, Živa Brenčič, Arianna Moiani, Audrey Michaud, Ivaylo Vassilev, Michel Wassef, Nicolas Servant, Bruno Sargueil, Raphaël Margueron (2017 Feb 8)
PRC2 is dispensable for HOTAIR-mediated transcriptional repression.
The EMBO journal : DOI : e201695335Year of publication 2016
Marie Schoumacher, Stéphanie Le Corre, Alexandre Houy, Eskeatnaf Mulugeta, Marc-Henri Stern, Sergio Roman-Roman, Raphaël Margueron (2016 Jun 9)
Uveal melanoma cells are resistant to EZH2 inhibition regardless of BAP1 status.
Nature medicine : 577-8 : DOI : 10.1038/nm.4098Year of publication 2015
Serena Sanulli, Neil Justin, Aurélie Teissandier, Katia Ancelin, Manuela Portoso, Matthieu Caron, Audrey Michaud, Berangère Lombard, Simao T da Rocha, John Offer, Damarys Loew, Nicolas Servant, Michel Wassef, Fabienne Burlina, Steve J Gamblin, Edith Heard, Raphaël Margueron (2015 Mar 5)