Philippe Benaroch, PhD


Philippe Benaroch Chef d'équipe Team BioPhenics Team Leader Scientific Director Tel: Back to the list

Key publications

Year of publication 2020

Ester Gea-Mallorquí, Laurent Zablocki-Thomas, Mathieu Maurin, Mabel Jouve, Vasco Rodrigues, Nicolas Ruffin, Philippe Benaroch (2020 Aug 6)

HIV-2-Infected Macrophages Produce and Accumulate Poorly Infectious Viral Particles.

Frontiers in microbiology : 1603 : DOI : 10.3389/fmicb.2020.01603
Laurent Zablocki-Thomas, Sam A Menzies, Paul J Lehner, Nicolas Manel, Philippe Benaroch (2020 Apr 7)

A genome-wide CRISPR screen identifies regulation factors of the TLR3 signalling pathway.

Innate immunity : 459-472 : DOI : 10.1177/1753425920915507

Year of publication 2019

Nicolas Ruffin, Ester Gea-Mallorquí, Flavien Brouiller, Mabel Jouve, Aymeric Silvin, Peter See, Charles-Antoine Dutertre, Florent Ginhoux, Philippe Benaroch (2019 Oct 9)

Constitutive Siglec-1 expression confers susceptibility to HIV-1 infection of human dendritic cell precursors.

Proceedings of the National Academy of Sciences of the United States of America : 21685-21693 : DOI : 10.1073/pnas.1911007116
Emiliano Roselli, Paula Araya, Nicolás Gonzalo Núñez, Gerardo Gatti, Francesca Graziano, Christine Sedlik, Philippe Benaroch, Eliane Piaggio, Mariana Maccioni (2019 Apr 6)

TLR3 Activation of Intratumoral CD103 Dendritic Cells Modifies the Tumor Infiltrate Conferring Anti-tumor Immunity.

Frontiers in immunology : 503 : DOI : 10.3389/fimmu.2019.00503
Vasco Rodrigues, Philippe Benaroch (2019 Mar 23)

Macrophages hide HIV in the urethra.

Nature microbiology : 556-557 : DOI : 10.1038/s41564-019-0418-5

Year of publication 2017

Jérémie Decalf, Marion Desdouits, Vasco Rodrigues, François-Xavier Gobert, Matteo Gentili, Santy Marques-Ladeira, Célia Chamontin, Marylène Mougel, Bruna Cunha de Alencar, Philippe Benaroch (2017 May 12)

Sensing of HIV-1 Entry Triggers a Type I Interferon Response in Human Primary Macrophages.

Journal of virology : DOI : e00147-17
Peter See, Charles-Antoine Dutertre, Jinmiao Chen, Patrick Günther, Naomi McGovern, Sergio Erdal Irac, Merry Gunawan, Marc Beyer, Kristian Händler, Kaibo Duan, Hermi Rizal Bin Sumatoh, Nicolas Ruffin, Mabel Jouve, Ester Gea-Mallorquí, Raoul C M Hennekam, Tony Lim, Chan Chung Yip, Ming Wen, Benoit Malleret, Ivy Low, Nurhidaya Binte Shadan, Charlene Foong Shu Fen, Alicia Tay, Josephine Lum, Francesca Zolezzi, Anis Larbi, Michael Poidinger, Jerry K Y Chan, Qingfeng Chen, Laurent Rénia, Muzlifah Haniffa, Philippe Benaroch, Andreas Schlitzer, Joachim L Schultze, Evan W Newell, Florent Ginhoux (2017 May 6)

Mapping the human DC lineage through the integration of high-dimensional techniques.

Science (New York, N.Y.) : DOI : eaag3009

Year of publication 2013

Stefano Berre, Raphaël Gaudin, Bruna Cunha de Alencar, Marion Desdouits, Mélanie Chabaud, Nadia Naffakh, Marc Rabaza-Gairi, François-Xavier Gobert, Mabel Jouve, Philippe Benaroch (2013 Oct 21)

CD36-specific antibodies block release of HIV-1 from infected primary macrophages and its transmission to T cells.

The Journal of experimental medicine : 2523-38 : DOI : 10.1084/jem.20130566
Raphaël Gaudin, Bruna Cunha de Alencar, Nathalie Arhel, Philippe Benaroch (2013 Apr 8)

HIV trafficking in host cells: motors wanted!

Trends in cell biology : 652-62 : DOI : 10.1016/j.tcb.2013.09.004

Year of publication 2012

Raphaël Gaudin, Bruna Cunha de Alencar, Mabel Jouve, Stefano Bèrre, Emmanuel Le Bouder, Michael Schindler, Aditi Varthaman, François-Xavier Gobert, Philippe Benaroch (2012 Oct 22)

Critical role for the kinesin KIF3A in the HIV life cycle in primary human macrophages.

The Journal of cell biology : 467-79 : DOI : 10.1083/jcb.201201144
Alejandra Garcia-Cattaneo, François-Xavier Gobert, Mélanie Müller, Florent Toscano, Marcella Flores, Aurianne Lescure, Elaine Del Nery, Philippe Benaroch (2012 May 18)

Cleavage of Toll-like receptor 3 by cathepsins B and H is essential for signaling.

Proceedings of the National Academy of Sciences of the United States of America : 9053-8 : DOI : 10.1073/pnas.1115091109

Year of publication 2009

Matias Ostrowski, Nuno B Carmo, Sophie Krumeich, Isabelle Fanget, Graça Raposo, Ariel Savina, Catarina F Moita, Kristine Schauer, Alistair N Hume, Rui P Freitas, Bruno Goud, Philippe Benaroch, Nir Hacohen, Mitsunori Fukuda, Claire Desnos, Miguel C Seabra, François Darchen, Sebastian Amigorena, Luis F Moita, Clotilde Thery (2009 Aug 14)

Rab27a and Rab27b control different steps of the exosome secretion pathway.

Nature cell biology : 19-30; sup pp 1-13 : DOI : 10.1038/ncb2000

Year of publication 2013

Raphaël Gaudin, Stefano Berre, Bruna Cunha de Alencar, Jérémie Decalf, Michael Schindler, François-Xavier Gobert, Mabel Jouve, Philippe Benaroch (1970 Jan 1)

Dynamics of HIV-containing compartments in macrophages reveal sequestration of virions and transient surface connections.

PloS one : e69450 : DOI : 10.1371/journal.pone.0069450